The Climate Pollution Reduction Grant (CPRG) program presents a historic opportunity for states and municipalities to develop and implement pollution reduction plans. The industrial sector is one of the nation’s largest sources of emissions, and jurisdictions can maximize the impact of CPRG funds by taking a holistic approach to emission reductions in the sector. This document offers a framework for applying such a holistic approach to the industrial sector and lists examples of concrete measures applicable to the industrial sector overall and high-emitting subsectors.